Dutahair Fortune

$21.00

Manufacturer: Fortune Substance: Dutasteride (Avodart) Pack: 0.5mg (15 capsules)

Additional information

Manufacturer

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Substance

Dutahair Fortune (Dutasteride) is a bivalent 5α-reductase inhibitor. Suppresses the activity of 5α-reductase isoenzymes of the 1 st and 2 nd types, which are responsible for the conversion of testosterone into 5α-dihydrotestosterone (DHT). Dihydrotestosterone is the main androgen responsible for hyperplasia of the glandular tissue of the prostate gland.

Effect on the concentration of dihydrotestosterone and testosterone. The maximum effect of dutasteride on the decrease in the concentration of dihydrotestosterone is dose-dependent and is observed 1-2 weeks after the start of treatment. After 1 and 2 weeks of taking dutasteride at a dose of 0.5 mg / day, the median values ​​of dihydrotestosterone concentrations in serum are reduced by 85% and 90%, respectively.

Dutasteride and hyperplasia treatment

At present, dutasteride is approved for the treatment of prostatic hyperplasia and is claimed to be a more effective analogue of finasteride (94.7% versus 70.8% over 4 months of [Clark] administration); testing of its effectiveness and safety for the correction of hirsutism in women continues. In theory, being an inhibitor of 5α-reductase type 1, 2, and 3, dutasteride is much more suitable for the treatment of hirsutism than finasteride, active against type 2α and 3α reductase. The reason is that type 1 5α-reductase enzyme is localized just in the skin, and type 2 is located in the skin of the scalp. Therefore, the use of finasteride for the treatment of hair loss is justified, but in the treatment of hirsutism is not very.

Side effects

Impotence, change (decrease) of libido, violation of ejaculation, gynecomastia (includes soreness and enlargement of the mammary glands).
Very rarely: an allergic reaction (rash, itching, hives, localized edema).

Overdose

In case of an overdose (80 times higher than the therapeutic dose), no side effects were noted.

There is no specific antidote for dutasteride, and therefore, if there is a suspicion of an overdose, it is sufficient to carry out symptomatic and supportive treatment.

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